The topics of cephalopod welfare and pending federal regulation of their use in laboratories continue to generate broad interest within the scientific community. This week The Trasnmitter published a detailed and nuanced article looking at the current state of knowledge in the field of welfare, and how this might affect or hinder the effective implementation of federal oversight. The story contains quotes from many cephalopod researchers with an interest in welfare, and quotes PI Robyn Crook extensively on what is needed to establish empirically-supported regulations and oversight. The Crook Lab is strongly in favor of additional oversight of cephalopod research, and it is our work on anesthesia. analgesia and affective state that is heavily informing this current effort.